The project, funded by the Ministry of University and Research (MUR) through the 2022 Ordinary Fund for Research Institutions (FOE), is titled "ACTIVE AGING AND HEALTH" (INV-ACT). Led by the CNR Department of Biomedical Sciences, the project aims to implement methodologies for aging studies along four main directions:
MOLECULAR AND CELLULAR MECHANISMS OF AGING
CLINICAL AND INSTRUMENTAL INDICATORS FOR ASSESSING THE HEALTH STATUS OF THE ELDERLY
INNOVATIVE THERAPEUTIC APPROACHES TO PROMOTE ACTIVE AGING
NUTRACEUTICALS FOR THE PREVENTION OF PATHOLOGICAL AGING
The IMEM Institute is involved in Task 1 of WP1.10: "Innovative methodologies for aging analysis and associated pathologies," which is part of the first research line (MOLECULAR AND CELLULAR MECHANISMS OF AGING). Within this framework, IMEM is working on the development of biosensors based on an organic transistor architecture known as Organic Electrochemical Transistor (OECT), optimized for the selective detection of molecular markers related to the monitoring of aging-related diseases.
OECTs allow the detection of biomarkers at sensitivities necessary for monitoring concentrations at the body's basal levels. The feasibility of these sensors is supported by previously achieved and published results. These devices, leveraging state-of-the-art sensitivity and functionalized with bioreceptors such as antibodies and/or aptamers, aim to achieve the desired selectivity.
Research Units:
- Institutes of the CNR DSB-Department of Biomedical Sciences (IGM, IBPM, IBB, IBBC, IRGB, IFC, IEOS, IN, ITB, IFT, IRIB, IBIOM)
- IMEM of the CNR DIITET-Department of Engineering, ICT and Technology for Energy and Transport
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